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About the Product

  • Gluten Free IMMUNE SYSTEM BOOSTER with No Artificial Flavours.
  • Natural Elements Helps fight free radicals, promotes normal cell growth & aid in your body's natural detoxification.
  • Reduce STRESS and FATIGUE and Boosts Your Immune system defense.
  • Helps overcome Respiratory Infections, Cold and Flu and ALLERGIES
  • ONLY 2-Softgels per-day, easy-to-swallow - Made in USA facilities registered and inspected by the FDA - GMP best quality standards - 60 Softgels bottle.

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Product Information

BESTFACTOR NATURALLY PRIMES THE KEY IMMUNE CELLS to help you INCREASE HEALTH and WELLNESS, promotes HEALTHY ENERGY, VIGOR, MENTAL CLARITY and VITALITY in TIMES of STRESS - protects the body from infectious diseases - REDUCE FATIGUE - RELIEF ALLERGY SUFFERER - REDUCE RESPIRATORY INFECTIONS and IMPROVE ATHLETIC PERFORMANCE. BESTFACTOR PLUS is a special product, which CONTAINS INGREDIENTS like MANUKA HONEY extracted in New Zealand. Numerous studies show its ANTIBACTERIAL POWER making it unique. Manuka honey ACTS AS A NATURAL ANTIBIOTIC AS WELL AS ANTIMICROBIAL, ANTIVIRAL AND ANTIOXIDANT. BESTFACTOR PLUS also has COLOSTRUM. It is the first mammary secretion derived from mother to child, which is FULL OF IMMUNOGLOBULINS PROTEIN. Colostrum transmits the antibodies from mother to child. Through this way, with BESTFACTOR Plus, we're getting back this protection to INCREASE OUR IMMUNE RESPONSE, creating a BETTER BALANCE IN OUR HORMONAL and DIGESTIVE SYSTEM and INCREASING MUSCLE STRENGTH. Another important ingredient of BESTFACTOR PLUS is the WELLMUNE® which is a natural ingredient that is derived from a proprietary strain of yeast. Numerous HUMAN CLINICAL STUDIES with Wellmune demonstrate its ability to ALLEVIATE THE HARMFUL EFFECTS OF BOTH PHYSICAL AND PSYCHOLOGICAL STRESS. The Wellmune ASSIST ATHLETES EVERY STEP OF THE WAY BEFORE, DURING AND AFTER EXERCISE. By adding OTHER INGREDIENTS such as VITAMINS (C, D, E) and MINERALS(Zinc), BESTFACTOR PLUS makes a very effective supplement that COVERS A BROAD SPECTRUM, protecting and improving the health of their consumers with ONLY 2 SOFTGELS a day. SOFTGELS ARE THE BEST presentation in the market OFFERING BETTER AND FASTER ABSORPTION OF THE PRODUCT, which is made in USA facilities registered and inspected by the FDA, laboratory tested, free of artificial flavors, free of genetically modified organisms(GMO-free) and gluten free. BESTFACTOR PLUS ESTABLISHES A NEW LIFESTYLE BY PROMOTING HEALTH, PROTECTION, AND ACTIVITY.

Product Details

Product Dimensions:   2.4 x 2.4 x 4.4 inches
Shipping Weight:   4 ounces
UPC:   867715000004
Average Customer Review:   5 out of 5 stars



This healing honey has been known to New Zealand's indigenous cultures for thousands of years. Manuka honey contains anti-bacterial properties, and in a study conducted by the University of Sydney killed nearly every type of bacteria it was exposed to. In 2004 Britain's National Health Service (NHS) licensed the use of medical grade Manuka honey as a wound dressing, confirming what the indigenous people of NZ have long known that Manuka honey is an impressive product with valuable properties.

Manuka honey is made by bees that feed on the flowers of the Manuka bush, also known as the Tea tree, in New Zealand. In recent tests conducted at Sydney University's School of Molecular and Microbial Biosciences, Manuka honey killed every type of bacteria, including antibiotic-resistant "superbugs". The University of Waikato in New Zealand has formed the Waikato Honey Research Unit to study the composition of honey and its antimicrobial activity.

The curative properties of honey have been known to indigenous cultures for thousands of years, and dressing wounds with honey was common before the advent of antibiotics. New Zealand's Maori were the first to identify the healing properties of Manuka and some of their remedies and tonics are still used today. The finest-quality Manuka honey, with the most potent antimicrobial properties, is produced from hives in wild, uncultivated areas.


  • Manuka honey has an antibacterial component that sets it apart from other honeys. This activity is stable and doesn't lose its potency when exposed to dilution, heat, or light.
  • Manuka honey has been found to be effective against a range of bacteria including Helicobacter Pylori (which causes most stomach ulcers); Escherichia Coli (the most common cause of infected wounds) and Streptococcus Pyogenes (which causes sore throats).
  • Manuka honey is antimicrobial and antiviral. It is also an antioxidant that can help to increase vitality and immunity.


Colostrum is not milk. It is the first mammary secretion derived from mother to child, available only for the first hours after a mammal gives birth. The colostrum available on the market is derived from Cows, and contains Immunoglobulin protein factors involved in boosting the human's:

  1. Immunity
  2. Digestive System
  3. Balancing Hormonal system
  4. Muscle strength and recovery

Colostrum is one of the very rare, natural products that contains Immunoglobulin-factors that are involved in promoting almost every system in the body, from immunity, to digestion, etc. It is one of the only natural substances that contains these factors because of its design to help kickstart life – this is why it is only produced in the first hours after birth: to strengthen, balance, and startup all the systems in the new born child.

Colostrum is produced in very small quantities compared to milk, and the quality of Colostrum will depend on important aspects of the following questions:

  1. What is the Immunoglobulin Concentration ? (must be 30%)
  2. Where is the Colostrum from? (Must be from cows in USA or New Zealand)
  3. What are the cows fed? (Must be natural grass)
  4. When is Colostrum collected? (Optimally within the first 12hours)
  5. How is it processed? (In order to avoid contamination, it must be processed in an FDA registered facility)

These aspects are critical because it is very easy to dilute, spoil, contaminate, and lower the quality of Colostrum, which relates directly to its Immunoglobulin content which must be 30%.

A strong immune system is integral to overall health and well being. The concept of boosting immunity is gaining in popularity because today’s complex world presents many potential health challenges – from environmental pollution and an increase in asthma and allergies, to the harmful effects of lifestyle stress and the effects of intense physical workouts on the body’s natural ability to stay well.

Not all immune boosters are created equally or are safe for everyday use. Some boosters on the market may artificially stimulate the immune system, which can have harmful effects particularly if used too long. Others lack the rigorous clinical research to support their health claims; there may be no understanding of how the booster works or an appropriate serving size for optimal benefit.

The science and safety behind Wellmune are strong. By taking clinically proven effective Wellmune every day, consumers can take a proactive approach to keeping their immune system healthy, while knowing that they are using a natural immune booster based on sound science.

Wellmune isn’t an immune stimulator. It does not put the key immune cells called neutrophils into overdrive. It only prepares them to be ready to respond to a foreign challenge.

Wellmune is the result of more than $300 million in research. It is proven safe and effective for everyone in the family.

For consumers who want to keep their immune system strong, they can keep pace with their busy lifestyle while adding supplements with Wellmune to their diet, which is a safely, proven effective way.

How Does Wellmune Work?

Wellmune® is a natural yeast beta 1,3/1,6 glucan derived from the cell wall of a highly purified, proprietary strain of baker’s yeast (Saccharomyces cerevisiae). This unique immune boosting ingredient triggers human immune defenses that have evolved over thousands of years to protect the body.

The scientific understanding of Wellmune’s mechanism of action in the body is well documented in published, peer-reviewed research. Mechanism of action studies as well as measurement of significant changes in immune responses are changing the way the scientific community thinks about innate immune function.

Once swallowed, immune cells in the gastrointestinal tract take up Wellmune and transport it to immune organs throughout the body. While in the immune organs, immune cells called macrophages digest Wellmune into smaller fragments and slowly release them over a number of days. The fragments bind to neutrophils, via complement receptor 3 (CR3), which are the most abundant immune cells in the body. In fact, neutrophils account for 60-70% of all immune cells.

Wellmune primes and strengthens the key immune function of neutrophils that now, more quickly, move throughout the body. Unlike other immune health ingredients, Wellmune boosts immune function without over stimulating the immune system.

Researchers discovered the mechanism through a series of experiments, including those with CR3-deficient-mice that confirmed the critical role this receptor plays in triggering an immune response. Other studies tracked fluorescently dyed Wellmune as immune cells transported it throughout the body or measured significant improvements in immune defense.

Immune-Boosting Benefits: Stress Management

Stress is on the rise. A study from Carnegie Mellon University reports that stress levels have increased 18% for women and 25% for men over the past 25 years. The 2012 Stress in America™ survey from the American Psychological Association found that nearly 7 in 10 women say they live with unhealthy stress levels. These sustained stress levels are concerning.

Stress is linked to many health problems, including suppression of the immune system. Stress may prematurely age the immune system and can enhance the risk of illness as well as age-related diseases. It is also associated with increased upper respiratory tract infection symptoms such as cold and flu.

While acute or short-term stress can enhance immune response, chronic or long-term stress can suppress immunity in several ways.

Numerous human clinical studies with Wellmune demonstrate its ability to alleviate the harmful effects of both physical and psychological stress. Clinical studies in high-stress populations, including firefighters, medical students, and people with high-stress lifestyles, found that Wellmune maintained overall physical health and reduced the incidence, and in some cases the duration of upper respiratory tract infection symptoms.

In addition to these physical health benefits, the clinical studies also demonstrated that Wellmune provides psychological benefits. Wellmune enhanced vigor and mental clarity of study subjects while reducing tension and fatigue. Participants taking Wellmune reported feeling better about their overall health than those in the placebo groups.

Immune-Boosting Benefits: Sports Nutrition

“For athletes, missing the chance to train is just as big a deal as missing a game(man games missed). In season, you fall off the goal of maintenance. Off season, you fall behind the goal of net progress! Great programs stay focused on out-working the competition with recovery keys like sound sleep, lifestyle, recovery therapies and nutrition. Wellmune is one of the better researched immune interventions we have in our toolbox to help ensure athletes don’t miss a chance to stay well – and in the game!” – Dave Ellis, RD, CSCS, Biothera Healthcare Scientific Advisory Board Immune Support and Sports Performance

Staying healthy is critical for effective training for elite, competitive, and active athletes. Studies consistently demonstrate that Wellmune can help support the overall health of an athlete by providing immune support. Thus, athletes can reap the immune health benefits of safe and clinically proven Wellmune.

Protein and recovery products may help rebuild muscles and replace depleted nutrients, but they don’t always compensate for the temporary weakening of the immune system that results from high intensity exercise. Those hard workouts can create an “open window” in the body’s defenses that may derail training programs and performance gains. Wellmune helps support the immune system to endure even through the toughest workout routines.

When taken as recommended for everyday immune support, Wellmune is there to assist athletes every step of the way before, during and after exercise. Multiple published, clinical studies have found that Wellmune reduced the incidence of upper respiratory tract infection symptoms that commonly afflict distance runners and other athletes.

In addition, as evidenced by these studies, athletes who have taken Wellmune have reported statistically significant higher levels of vigor, less fatigue and greater ability to focus.

Another one of our scientific advisors, Joy Dubost, Ph.D., RD, CSSD, who is also a competitive figure skater, had this to say about immune support for athletes in the April 2013 issue of Today’s Dietitian. The article is titled, “Ergonomic Aids – Competitive Edge or Hidden Danger” written by Constance Brown-Riggs, MSEd, RD, CDE, CDN.

“We forget that athletes are immune compromised because of the stress of training. They need education on the proper diet and supplementation to support good immune function.”

The article went on to note that Dr. Dubost’s “…biggest fear is not feeling well on the day of her skating competition. To ensure she maintains her competitive edge, she includes an immune supplement in her daily routine.”

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Immune-Boosting Benefits: Healthy Aging

The immune system weakens with age, a process called immunosenescence. The body produces fewer immune cells, communication between cells break down and responses to health challenges. The slow decline of immune function can significantly impact overall health, vitality and appearance.

Wellmune is clinically proven to strengthen the immune system. It boosts billions of immune cells that help keep the body healthy. Wellmune-activated immune cells are ready to respond more quickly as needed, helping to support the immune system as we age. Wellmune is a safe and effective ingredient for those concerned about healthy aging.


Vitamin C is one of the safest and most effective nutrients, experts say. It may not be the cure for the common cold, but it's thought to help prevent more serious complications. The benefits of Vitamin C may include protection against immune system deficiencies, cardiovascular disease, prenatal health problems, eye disease, and even skin wrinkling.

A recent study published in Seminars in Preventive and Alternative Medicine that looked at over 100 studies over 10 years
revealed a growing list of benefits of Vitamin C.

"Vitamin C has received a great deal of attention, and with good reason. Higher blood levels of Vitamin C may be the ideal nutrition marker for overall health," says study researcher Mark Moyad, MD, MPH, of the University of Michigan. "The more we study Vitamin C, the better our understanding of how diverse it is in protecting our health from cardiovascular, cancer, stroke, eye health and immunity to living longer."


Vitamin D has several important functions. Perhaps the most vital are regulating the absorption of calcium and phosphorous, and facilitating normal immune system function. Getting a sufficient amount of the vitamin is important for normal growth and development of bones and teeth, as well as improved resistance against certain diseases.

If your body doesn’t get enough Vitamin D, you’re at risk of developing bone abnormalities such as osteomalacia (soft bones) or osteoporosis (fragile bones).

In addition to its primary benefits, research suggests that Vitamin D may also play a role in:

  • reducing your risk of multiple sclerosis, according to a 2006 study published in the Journal of the American Medical Association.
  • decreasing your chance of developing heart disease, according to 2008 findings published in Circulation.
  • helping to reduce your likelihood of developing the flu, according to 2010 research published in the American Journal of Clinical Nutrition.


Vitamin E is key for strong immunity and healthy skin and eyes. In recent years, Vitamin E supplements have become popular as antioxidants. These are substances that protect cells from damage.

Many people use Vitamin E supplements in the hopes that the vitamin's antioxidant properties will prevent or treat disease.


Zinc is needed for the proper growth and maintenance of the human body. It is found in several systems and biological reactions, and it is needed for immune function, wound healing, blood clotting, thyroid function, and much more.

Athletes use zinc for improving athletic performance and strength.

Zinc plays a key role in maintaining vision, and it is present in high concentrations in the eye. Zinc deficiency can alter vision, and severe deficiency can cause changes in the retina (the back of the eye where an image is focused).

Zinc might also have effects against viruses. It appears to lessen symptoms of the rhinovirus (common cold), but researchers can’t yet explain exactly how this works. In addition, there is some evidence that zinc has some antiviral activity against the herpes virus.


Citrus fruits are well known for providing ample amounts of Vitamin C, but they also supply bioflavonoids, which are substances that are not required for life, but that may improve health.

The citrus Bioflavonoids may also be helpful for chronic venous insufficiency, a condition in which the veins in the legs begin to weaken.

In addition, highly preliminary evidence suggests that citrus bioflavonoids may help reduce cholesterol levels, control inflammation and reduce allergic reactions.

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